Histomer Hisiris Pro Dermis Active Cream – Intensive Soothing Moisturiser for Sensitive & Reactive Skin
A clinically formulated day cream from Histomer, the Italian clinical skincare brand. Part of the Hisiris Pro Dermis line, designed specifically for constitutionally sensitive skin prone to allergic reactions, irritation, and environmental reactivity. Soothes flare-ups, deeply hydrates, and progressively strengthens the skin barrier, so skin becomes more resilient over time, not just temporarily calmed. Hypoallergenic and dermatologically tested.
Key actives and what they do
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Niacinamide (Vitamin B3) — One of the most well-researched actives for sensitive and reactive skin. Strengthens the skin barrier by stimulating ceramide production — the lipids that hold the barrier together and prevent moisture loss. Reduces transepidermal water loss, calms redness and blotchiness, and reduces the skin’s reactivity to environmental triggers over time. Also inhibits melanin transfer, progressively evening skin tone with consistent use. Niacinamide is one of the few potent actives that is genuinely well-tolerated by sensitive skin — it does not cause irritation or a purging period.
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Chamomile Extract (Bisabolol) — A clinically recognized anti-inflammatory active derived from chamomile. Bisabolol reduces redness, calms itching and burning, and soothes the skin’s inflammatory response during and after sensitivity flare-ups. Also supports wound healing and skin barrier repair. One of the most effective botanical actives for reactive skin — gentle enough for daily use even on the most sensitive skin types.
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Hyaluronic Acid — A humectant that draws moisture into the skin and holds it there. Sensitive skin loses moisture more rapidly than normal skin due to barrier compromise — hyaluronic acid restores surface hydration, plumps fine lines, and maintains skin comfort throughout the day without triggering reactivity.
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Shea Butter — A rich emollient that seals moisture into the skin and smooths the skin surface. Provides a protective occlusive layer that reduces the skin’s exposure to environmental irritants — particularly effective for skin that reacts to wind, dust, and temperature changes. Non-comedogenic and well-tolerated by sensitive skin.
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Hisiris Desensitizing Complex — Histomer’s proprietary blend of desensitizing and anti-inflammatory agents. Reduces the skin’s reactivity threshold progressively — with consistent use, the skin becomes less likely to react to environmental triggers, cosmetic products, and temperature changes. The defining active of the Hisiris range.
What to expect
Immediate: redness, tightness, and irritation are visibly calmed after the first application. Skin feels hydrated and comfortable without heaviness or greasiness. With consistent daily use over 4–8 weeks: progressive strengthening of the skin barrier, reduced frequency and intensity of sensitivity reactions, improved skin tone evenness, and a more resilient complexion. Particularly effective in the UAE, where the daily contrast between outdoor heat and air-conditioned interiors repeatedly disrupts the skin barrier and triggers reactivity in sensitive skin.
Who it is for
- Constitutionally sensitive skin prone to irritation, allergic reactions, and environmental reactivity
- Skin that reacts to most skincare products, weather changes, or stress
- Anyone seeking a hypoallergenic daily moisturiser that actively strengthens the skin barrier
- All ages — sensitivity is not age-dependent
- All skin types with sensitivity concerns — dermatologically tested
Who it is not for
- Sensitive vascular skin with redness, couperose, or rosacea — use Hisiris Pro Rose instead
- Mature sensitive skin with dryness, fragility, and loss of tone — use Hisiris Pro Age instead
- Anyone looking for an anti-aging day cream — this formula prioritizes soothing and barrier repair over anti-aging actives
About the Hisiris line
The Hisiris range by Histomer addresses different forms of skin sensitivity with three targeted sub-lines. Pro Dermis is for constitutionally sensitive skin prone to irritation and allergies. Pro Rose is for sensitive vascular skin with redness, couperose, or rosacea. Pro Age is for mature skin prone to dryness, fragility, and loss of tone. Each sub-line uses the same Hisiris desensitizing complex as its foundation, with additional actives tailored to the specific sensitivity type.
Clinical skincare by Histomer. Made in Italy. Hypoallergenic. Dermatologically tested. For external use only. Avoid contact with eyes.
1 - Apply a small amount of cream to cleansed face and neck every morning.
2 - Spread evenly with gentle, upward strokes.
3 - Massage until completely absorbed, leaving skin moisturised and protected throughout the day.
4 - For a complete treatment, combine with Night Repair Dermal Cream in the evening.
Aqua, Propylheptyl Caprylate, Cocoglycerides, Pentylene Glycol, Cetearyl Isononanoate, Cetearyl Alcohol, Arachidyl Alcohol, Glycerin, Olea Europaea Fruit Oil, Glyceryl Stearate, Butyrospermum Parkii Butter, Coco-Caprylate, Behenyl Alcohol, Tocopheryl Acetate, Acetyl Tetrapeptide-15, Ellagic Acid, Boswellia Serrata Gum, Anogeissus Leiocarpa Bark Extract, Syringa Vulgaris Leaf Cell Culture Extract, Gardenia Jasminoides Meristem Cell Culture, Sodium Hyaluronate, Caprylyl Glycol, Brassica Campestris Sterols, Dipropylene Glycol, Lecithin, Methylpropanediol, Propanediol, Lauric Acid, Dimethicone, Arachidyl Glucoside, Phenoxyethanol, Polyacrylate Crosspolymer-6, Potassium Cetyl Phosphate, Parfum, Glycerophosphoinositol Choline, 4-t-Butylcyclohexanol, Mannitol, Caprylhydroxamic Acid, Xanthan Gum, Piroctone Olamine, Tetrasodium Glutamate Diacetate, Lauryl Alcohol, Diphosphonic Acid, Tocopherol, Maltodextrin, Ascorbyl Palmitate, Sodium Citrate, Citric Acid