Histomer BIO HLS Vital Filler – Anti-Aging Day Cream with SPF 10 | 45–55 Skin | 50ml

Histomer BIO HLS Vital Filler – Anti-Aging Day Cream with SPF 10 | 45–55 Skin 

A 24-hour bio-stimulant anti-aging day cream from Histomer, the Italian clinical skincare brand. Formulated specifically for skin aged 45–55, the turning point when collagen production declines, expression lines deepen, and early sagging begins. Powered by Gardenia Jasminoides stem cells and the proprietary Bio-HLS Vital Complex to stimulate hyaluronic acid and collagen production from within. Targets both the reticular and papillary dermis for deep, structural improvement. Built-in SPF 10 for daily photoaging protection.

Clinical results after 28 days

• 32% reduction in fine lines and wrinkles
• 38% improvement in skin elasticity
• 29% increase in hydration levels
• Visibly smoother, more youthful appearance

Key actives and what they do

• Gardenia Jasminoides Stem Cells — Plant stem cells with exceptional regenerative properties. Protect the skin’s own stem cell population from oxidative stress and UV damage, supporting the skin’s natural renewal capacity. Improve radiance and contribute to a more even, luminous complexion. A key active across the BIO HLS range.
• Bio-HLS Vital Complex — Histomer’s proprietary bio-stimulant complex formulated for the 45–55 age window. Stimulates fibroblast activity — the skin cells responsible for producing collagen and elastin — to restore structural support from within. Targets both the reticular dermis (deep structural layer) and the papillary dermis (surface layer) for comprehensive anti-aging action.
• Hyaluronic Acid Stimulators — Rather than simply applying hyaluronic acid topically, the formula stimulates the skin’s own hyaluronic acid production. This delivers a more sustained plumping and hydration effect than surface-level HA application alone.
• SPF 10 — Daily photoprotection against UV-induced collagen breakdown and pigmentation. While SPF 10 is not sufficient as standalone sun protection in the UAE’s extreme UV environment, it provides meaningful additional defense when layered under a dedicated SPF 50+ product.

How it differs from BIO HLS Supreme Filler

Both are BIO HLS day creams with SPF 10, but they target different age windows and skin needs. Vital Filler is calibrated for skin aged 45–55, addressing early-to-mid signs of aging: declining collagen, deepening expression lines, and early sagging. Supreme Filler is calibrated for skin aged 55–65 and post-menopausal skin, addressing more advanced aging: deep wrinkles, significant firmness loss, and pronounced sagging. If you are between 45 and 55, start with Vital Filler. If you are 55+ or post-menopausal, Supreme Filler is the appropriate choice.

What to expect

Immediate: skin feels deeply hydrated and comfortable after the first application. Texture is rich but absorbs without heaviness. With consistent morning and evening use over 4–8 weeks: progressive improvement in firmness, reduction in fine line depth, and a visibly more even, plumper skin surface. The bio-stimulant complex works cumulatively, results build with each application rather than delivering a one-time surface effect.

Who it is for

• Women aged 45–55 experiencing early-to-mid signs of aging: deepening expression lines, loss of firmness, declining radiance
• Anyone seeking a non-invasive alternative to aesthetic treatments for structural skin improvement
• Anyone in the UAE climate where UV exposure and heat accelerate collagen breakdown and skin aging

Who it is not for

• Skin aged 55+ or post-menopausal — use BIO HLS Supreme Filler instead, which is calibrated for more advanced aging needs
• Younger skin (under 40) without significant firmness loss — the formula is calibrated for mature skin needs

About BIO HLS

Histomer’s BIO HLS line brings professional skin bio-stimulation into daily home skincare, delivering results comparable to aesthetic medicine without the clinic. Formulated with three high-penetration biological complexes and concentrated Gardenia and Buddleja Davidii stem cells for deep regeneration, firming, and anti-aging action. Suitable for home use and as a professional post-treatment protocol after bio-stimulation facials.

Clinical skincare by Histomer. Made in Italy. For external use only. Avoid contact with eyes.